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HomeVariants

chr17:41244296 AAGCAT>A

Annotations

GeneBRCA1
TranscriptNM_007294.3
cDNAc.3247_3251del
Proteinp.M1083fs
Functionframeshift del
Localizationexon
hg19chr17:41244296 AAGCAT>A
dbSNP

Synonyms

TranscriptcDNAProtein
NM_007297.3c.3106_3110delp.M1036fs
NM_007300.3c.3247_3251delp.M1083fs
NM_007298.3c.788-1252_788-1248delATGCT
NM_007299.3c.788-1252_788-1248delATGCT
NR_027676.1n.3383_3387delATGCT

Frequency in gnomAD

GenomeExome
MAX
AFR
AMR
ASJ
EAS
FIN
NFE
SAS

ClinVar

IDPhenotypeEffect
RCV000496619.2Hereditary breast and ovarian cancer syndromePathogenic
RCV000661066.1Breast-ovarian cancer, familial 1Pathogenic