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chr2:48027278 C>T

Annotations

GeneMSH6
TranscriptNM_000179.2
cDNAc.2156C>T
Proteinp.T719I
Functionmissense
Localizationexon
hg19chr2:48027278 C>T

Synonyms

TranscriptcDNAProtein
NM_001281492.1c.1766C>Tp.T589I
NM_001281493.1c.1250C>Tp.T417I
NM_001281494.1c.1250C>Tp.T417I

Frequency in gnomAD

GenomeExome
MAX0.000066630.000008997
AFR00
AMR00
ASJ00
EAS00
FIN00
NFE0.000066630.000008997
SAS0

ClinVar

IDPhenotypeEffect
RCV000214718.2Hereditary cancer-predisposing syndromeVUS
RCV000205525.3Hereditary nonpolyposis colon cancerVUS