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chr2:47690245 T>G

Annotations

GeneMSH2
TranscriptNM_000251.2
cDNAc.1462T>G
Proteinp.L488V
Functionmissense
Localizationexon
hg19chr2:47690245 T>G

Synonyms

TranscriptcDNAProtein
NM_001258281.1c.1264T>Gp.L422V
XR_001738747.1n.1534T>G
XR_939685.1n.1534T>G

Frequency in gnomAD

GenomeExome
MAX0.00003584
AFR0
AMR0
ASJ0
EAS0
FIN0
NFE0.00003584
SAS0.00003249

ClinVar

IDPhenotypeEffect
RCV000129044.5Hereditary cancer-predisposing syndromeConflicting interpretations of pathogenicity
RCV000656877.1not providedVUS
RCV000662760.1Lynch syndrome IVUS
RCV000199801.4Hereditary nonpolyposis colon cancerVUS
RCV000485646.3not specifiedVUS