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HomeVariants

chr17:41244839 A>T

Annotations

GeneBRCA1
TranscriptNM_007294.3
cDNAc.2709T>A
Proteinp.C903X
Functionstop gain
Localizationexon
hg19chr17:41244839 A>T
dbSNP

Synonyms

TranscriptcDNAProtein
NM_007297.3c.2568T>Ap.C856X
NM_007300.3c.2709T>Ap.C903X
NM_007298.3c.788-1790T>A
NM_007299.3c.788-1790T>A
NR_027676.1n.2845T>A

Frequency in gnomAD

GenomeExome
MAX
AFR
AMR
ASJ
EAS
FIN
NFE
SAS

ClinVar

IDPhenotypeEffect
RCV000585837.2Breast-ovarian cancer, familial 1Pathogenic
RCV000585811.2FANCONI ANEMIA, COMPLEMENTATION GROUP SPathogenic