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chr16:23614833 G>A

Annotations

GenePALB2
TranscriptNM_024675.3
cDNAc.3508C>T
Proteinp.H1170Y
Functionmissense
Localizationexon
hg19chr16:23614833 G>A

Frequency in gnomAD

GenomeExome
MAX0.000066650.00008952
AFR00
AMR00
ASJ00
EAS00
FIN00
NFE0.000066650.00008952
SAS0.00003249

ClinVar

IDPhenotypeEffect
RCV000212829.4not providedVUS
RCV000226949.4Familial cancer of breastVUS
RCV000129794.6Hereditary cancer-predisposing syndromeVUS

HGMD

IDPhenotypeEffect
CM189992Breast cancerDM?