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chr2:48033370 C>T

Annotations

GeneMSH6
TranscriptNM_000179.2
cDNAc.3674C>T
Proteinp.T1225M
Functionmissense
Localizationexon
hg19chr2:48033370 C>T

Synonyms

TranscriptcDNAProtein
NM_001281492.1c.3284C>Tp.T1095M
NM_001281493.1c.2768C>Tp.T923M
NM_001281494.1c.2768C>Tp.T923M

Frequency in gnomAD

GenomeExome
MAX0.00020.0001
AFR00
AMR00
ASJ00
EAS00.00005799
FIN00.00004486
NFE0.00020.0001
SAS0.00009746

ClinVar

IDPhenotypeEffect
RCV000074911.4Lynch syndromeVUS
RCV000160696.7Hereditary cancer-predisposing syndromeVUS
RCV000524182.2Hereditary nonpolyposis colon cancerVUS
RCV000212686.2not providedVUS
RCV000410774.1Hereditary nonpolyposis colorectal cancer type 5VUS