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chr11:108183151 G>T

Annotations

GeneATM
TranscriptNM_000051.3
cDNAc.5932G>T
Proteinp.E1978X
Functionstop gain
Localizationexon
hg19chr11:108183151 G>T

Synonyms

TranscriptcDNAProtein
NM_001351834.1c.5932G>Tp.Glu1978*
NM_001351835.1c.*83093G>T
NM_001351836.1c.*83093G>T

Frequency in gnomAD

GenomeExome
MAX0.00009858
AFR0
AMR0
ASJ0
EAS0
FIN0
NFE0.00009858
SAS0

ClinVar

IDPhenotypeEffect
RCV000515323.1Pathogenic
RCV000115219.8Hereditary cancer-predisposing syndromePathogenic
RCV000212035.3not providedPathogenic
RCV000205725.4Ataxia-telangiectasia syndromePathogenic

HGMD

IDPhenotypeEffect
CM980147Ataxia telangiectasiaDM