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HomeVariants

chr17:41245861 G>A

Annotations

GeneBRCA1
TranscriptNM_007294.3
cDNAc.1687C>T
Proteinp.Q563X
Functionstop gain
Localizationexon
hg19chr17:41245861 G>A

Synonyms

TranscriptcDNAProtein
NM_007297.3c.1546C>Tp.Q516X
NM_007300.3c.1687C>Tp.Q563X
NM_007298.3c.787+900C>T
NM_007299.3c.787+900C>T
NR_027676.1n.1823C>T

Frequency in gnomAD

GenomeExome
MAX0.00005396
AFR0
AMR0
ASJ0
EAS0
FIN0
NFE0.00005396
SAS0

HGMD

IDPhenotypeEffect
CM950144Breast cancerDM