Log in
HomeVariants

chr17:41244341 TTGAA>T

Annotations

GeneBRCA1
TranscriptNM_007294.3
cDNAc.3203_3206del
Proteinp.I1068fs
Functionframeshift del
Localizationexon
hg19chr17:41244341 TTGAA>T

Synonyms

TranscriptcDNAProtein
NM_007297.3c.3062_3065delp.I1021fs
NM_007300.3c.3203_3206delp.I1068fs
NM_007298.3c.788-1296_788-1293delTTCA
NM_007299.3c.788-1296_788-1293delTTCA
NR_027676.1n.3339_3342delTTCA

Frequency in gnomAD

GenomeExome
MAX
AFR
AMR
ASJ
EAS
FIN
NFE
SAS

ClinVar

IDPhenotypeEffect
RCV000257259.2Breast-ovarian cancer, familial 1Pathogenic