Log in
HomeVariants

chr2:48033775 C>T

Annotations

GeneMSH6
TranscriptNM_000179.2
cDNAc.3986C>T
Proteinp.S1329L
Functionmissense
Localizationexon
hg19chr2:48033775 C>T

Synonyms

TranscriptcDNAProtein
NM_001281492.1c.3596C>Tp.S1199L
NM_001281493.1c.3080C>Tp.S1027L
NM_001281494.1c.3080C>Tp.S1027L

Frequency in gnomAD

GenomeExome
MAX0.00010.0001
AFR00
AMR00
ASJ00
EAS00
FIN00
NFE0.00010.0001
SAS0

ClinVar

IDPhenotypeEffect
RCV000588490.1not providedVUS
RCV000524202.2Hereditary nonpolyposis colon cancerVUS
RCV000212693.3not specifiedConflicting interpretations of pathogenicity
RCV000115429.7Hereditary cancer-predisposing syndromeLikely benign
RCV000074965.4Lynch syndromeLikely benign